SYRE insider trading — Spyre Therapeutics, Inc.
No open-market insider purchases or sales were filed for Spyre Therapeutics, Inc. (SYRE) in the last 90 days. Other insider transactions — such as stock awards, option exercises or tax withholding — are listed below.
Updated Oct 16, 2026.
Recent SYRE insider transactions
Every Form 4 filed by Spyre Therapeutics, Inc. officers, directors and 10% owners in the last 90 days, newest first. P = open-market purchase, S = open-market sale; other codes are awards, option exercises, tax withholding or gifts.
| Trade date | Insider | Role | Type | Ownership | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| Oct 1, 2026 | King-Jones Heidy | See Remarks | M · Option exercise · 10b5-1 | Direct | 28,933 | $14.50 | $420K | Form 4 |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | S · Sale · 10b5-1 | Direct | 28,933 | $91.03 | $2.63M | Form 4 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | M · Option exercise · 10b5-1 | Direct | 7,500 | $14.50 | $109K | Form 4 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | S · Sale · 10b5-1 | Direct | 7,500 | $91.83 | $689K | Form 4 |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | S · Sale · 10b5-1 | Direct | 15,000 | $92.01 | $1.38M | Form 4 |
| Sep 30, 2026 | Burrows Scott L | Chief Financial Officer | M · Option exercise · 10b5-1 | Direct | 17,500 | $14.50 | $254K | Form 4 |
| Sep 30, 2026 | Burrows Scott L | Chief Financial Officer | S · Sale · 10b5-1 | Direct | 17,500 | $89.89 | $1.57M | Form 4 |
| Sep 2, 2026 | King-Jones Heidy | See Remarks | M · Option exercise · 10b5-1 | Direct | 400 | $14.50 | $6K | Form 4 |
| Sep 2, 2026 | King-Jones Heidy | See Remarks | S · Sale · 10b5-1 | Direct | 400 | $90.00 | $36K | Form 4 |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | M · Option exercise · 10b5-1 | Direct | 27,999 | $14.50 | $406K | Form 4 |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | S · Sale · 10b5-1 | Direct | 27,999 | $87.31 | $2.44M | Form 4 |
| Sep 2, 2026 | Burrows Scott L | Chief Financial Officer | S · Sale · 10b5-1 | Direct | 18,232 | $89.35 | $1.63M | Form 4 |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | M · Option exercise · 10b5-1 | Direct | 7,500 | $14.50 | $109K | Form 4 |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | S · Sale · 10b5-1 | Direct | 7,500 | $87.31 | $655K | Form 4 |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | S · Sale · 10b5-1 | Direct | 15,000 | $87.29 | $1.31M | Form 4 |
| Aug 7, 2026 | Albers Jeffrey W. | Director | M · Option exercise · 10b5-1 | Direct | 5,000 | $10.39 | $52K | Form 4 |
| Aug 7, 2026 | Albers Jeffrey W. | Director | S · Sale · 10b5-1 | Direct | 5,000 | $104.47 | $522K | Form 4 |
| Aug 7, 2026 | Albers Jeffrey W. | Director | S · Sale · 10b5-1 | Indirect | 18,000 | $104.55 | $1.88M | Form 4 |
| Aug 3, 2026 | Burrows Scott L | Chief Financial Officer | M · Option exercise · 10b5-1 | Direct | 7,500 | $14.50 | $109K | Form 4 |
| Aug 3, 2026 | Burrows Scott L | Chief Financial Officer | S · Sale · 10b5-1 | Direct | 7,500 | $95.57 | $717K | Form 4 |
| Aug 3, 2026 | Turtle Cameron | Chief Executive Officer | S · Sale · 10b5-1 | Direct | 15,000 | $95.51 | $1.43M | Form 4 |
SYRE insider trading FAQ
Are insiders buying SYRE stock?
Not on the open market. In the last 90 days, Spyre Therapeutics, Inc. insiders made no open-market purchases, and no open-market sales. Purchases with the insider's own money are generally seen as a stronger signal than sales, which happen for many reasons (taxes, diversification, planned 10b5-1 sales).
Who are the insiders trading SYRE?
No insider bought or sold on the open market in the last 90 days.
Where does SYRE insider trading data come from?
Every transaction comes from SEC Form 4 filings on EDGAR. Company officers, directors and 10% owners must file a Form 4 within two business days of buying or selling. InsiderBolt reads these filings directly from the SEC.
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Insider trading data is for informational purposes only and is not investment advice. Filings can be amended; always confirm details on SEC EDGAR.